Treatment and Management of HIV Infection in the United States

HIV THE BASICS

May 10-12, 2012
Sheraton Downtown Hotel
Denver, CO, US
www.ACTHIV.org

Friday, May 15, 2009 8:00 am - 11:30 am

Session Co-Chairs: Brian Feit, MPA, Department of Health and Human Services
Kenneth Mayer, MD, Brown University, Infectious Disease Division



Session Objectives:

  • Utilize appropriate clinical tests for guiding the care of individuals with HIV
  • Develop treatment strategies  for individuals with HIV based on currently available guidelines
  • Incorporate strategies for remaining up-to-date on future modifications to the guidelines for managing the care of those with HIV
  • Identify appropriate ARV regimens for newly diagnosed individuals with HIV based on current evidence

Session Outline:

8:10 am - 8:30 am History of the Epidemic:

  • Epidemiology: Global and Local
  • US – Then and Now 
  • Late presentation and reasons for routine HIV testing

Speaker: Ronald Valdiserri, MD, US Department of Veterans Affairs

8:30 am - 9:00 am

Natural History of HIV Infection—Pathogenesis

  • HIV Life Cycle
  • Cell Membrane Receptors and Viral Entry
  • Neutralizing Antibodies, CTLs and other host responses
  • Natural History of Untreated HIV
  • Stages of HIV Infection

Speaker:Rajesh Gandhi, MD, Massachusetts General Hospital

9:00 am - 9:30 am

Clinical Tests

  • What they are, What they tell you, Why to use them
  • HIV testing
  • Who to test, where to test, how to test?
  • Elisa
  • Western Blot
  • DNA/RNA testing
  • CD4 Counts
  • Viral Loads

Guidelines: Evolving Care/Changing guide

  • When to start treatment (borrow from the IAS and DHHS treatment Guidelines. In fact it could be a perk for the course – each person who attends gets a copy of the IAS and DHHS treatment guidelines in a binder.)
  • Building an Antiretroviral Regimen – Initiation of treatment
  • Where to get updates – AIDS Info
  • Summarize Opportunistic Infection Management Principles and Prophylaxis

Speaker: Paul Volberding, MD, San Francisco VA Medical Center

9:30 pm - 10:00am

Q&A / Break

10:00am - 10:30 am

Medications - Types of Antiretrovirals

  • NRTI (Indications, Benefits, Side effects)
  • NNRTI (Indications, Benefits, Side effects)
  • PI (Indications, Benefits, Side effects)
  • Fusion Inhibitors (Indications, Benefits, Side effects)
  • Integrase Inhibitors
  • New Agents on the horizon
  • Resistance Testing—Genotypic & Phenotypic
  • When to switch

Speaker: Richard D'Aquila, MD, Vanderbilt University

10:30 am - 11:00 am

Transmission/Prevention

  • Points of high infectivity, such as during the Acute Retroviral syndrome
  • Primary Prevention
  • Prevention with Positives
  • STDs
  • Post Exposure Prophylaxis
  • Prevention of Maternal To Child Transmission

Speaker: Mark Thrun, MD, Denver Health Medical Center

11:00 am - 11:30 am

 Consumer Perspective: If you build it, will they come? What consumers really want in care
Speaker: Dawn Averitt-Bridge, The Well Project