Treatment and Management of HIV Infection in the United States

Case Studies in PrEP and PEP:
A STEP-HIV Initiative

Release Date: January 7, 2016
Expiration Date: January 7, 2017
Estimated Time to Complete: 1.0 hours

Case Studies in PrEP and PEP:
A STEP-HIV Initiative

Activity URL:

Jointly Provided by:Support for this activity has been made possible through
an educational grant from Gilead Sciences

Activity Description
To achieve optimal health outcomes, people living with HIV require continuous access to quality care and treatment for HIV as well as for their other health conditions. (Institute of Medicine 2012) However at the same time, it has been documented that there are an insufficient number of health care professionals with the necessary expertise to care for the growing number of individuals living with HIV. (IOM 2011, Kirch 2012, Reif 2012)

This is the first in a series of Special Training for Effective Providers in HIV (STEP-HIV) initiatives developed by ACTHIV and the American Academy of CME, Inc. to promote HIV workforce development through education for healthcare professionals who are in training or who are in practice but are new to HIV medicine.

This activity will focus on pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP), providing a grounding in the data supporting these strategies and offering guidance on how to implement them in practice.

Activity Faculty

Renslow Sherer, MD
Professor of Medicine
University of Chicago

Faculty Bio

Renslow Sherer, MD serves as Professor of Medicine, Department of Medicine at the University of Chicago. He has extensive experience and expertise in HIV primary care and has been active in HIV clinical research and in the design and implementation of clinical trials, in HIV prevention programs, and in local and federal policy on HIV disease. Dr. Sherer has published extensively in the area of HIV and AIDS and has been a member of numerous committees, task forces and panels on AIDS. He is a member of several professional associations, including International AIDS Society, HIV Medicine Association, Infectious Disease Society of North America, and the Academy of HIV Medicine.

Activity Agenda

  • Review of Key Clinical Trials
  • Procedural Steps, including USPHS Guidance
  • Case Discussions and Q&A

Target Audience
This activity has been designed to meet the educational needs of physicians (both specialists and primary care/family medicine), nurses, nurse practitioners, and physician assistants who are in training or who are in practice but are new to HIV medicine. Other healthcare providers may also participate.

Learning Objectives
After participating in the activity, learners should be better able to:

  • Review the efficacy and limitations of pre-exposure prophylaxis (PrEP) in real world community settings;
  • Cite the required steps for PrEP implementation and follow up, including the role of adherence and psychosocial factors; and
  • Review the principles, drug options, and key clinical issues of post-exposure prophylaxis (PEP).

Accreditation and Credit Designation

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education through the joint providership of American Academy of CME, Inc., (Academy) and ACTHIV. American Academy of CME, Inc., is accredited by the ACCME to provide continuing medical education for physicians.

American Academy of CME, Inc., designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

American Academy of CME, Inc, is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on Accreditation.

American Academy of CME, Inc., designates this educational activity for 1.0 contact hours (1.0 Pharmacotherapeutic Contact Hours)

Disclosure Statement
According to the disclosure policy of the Academy, all faculty, planning committee members, editors, managers and other individuals who are in a position to control content are required to disclose any relevant relationships with any commercial interests related to this activity. The existence of these interests or relationships is not viewed as implying bias or decreasing the value of the presentation. All educational materials are reviewed for fair balance, scientific objectivity and levels of evidence. Disclosures are as follows:


  • Renslow Sherer, MD: No relevant financial relationships with any commercial interests.

Planning Committee

  • Sharon Lee, MD, Medical Director, Southwest Boulevard Family Health Care Services of Greater Kansas City, (Kansas); President, ACTHIV, discloses the following relationships: Advisory Board: Gilead Sciences, ViiV Healthcare
  • Kathleen E. Squires, MD, W. Paul and Ida H. Havens Professor of Infectious Diseases, Director, Division of Infectious Diseases, Sidney Kimmel Medical College, Thomas Jefferson University; Chairperson of the Board, ACTHIV: discloses the following relationships: Advisory Board for Scientific Information: Bristol Myers-Squibb, Gilead Sciences, Merck, Janssen, ViiV Healthcare; Consultant for Clinical Trial Design: Merck & Co.; Grant/Research Support: Gilead Sciences
  • John JD Juchniewicz, MCIS, CHCP, and Natalie Kirkwood, RN, BSN, JD, Lead Nurse Planner, American Academy of CME, Inc.: No relevant financial relationships with any commercial interests.

This activity will not review off-label or investigational information.

The opinions expressed in this educational activity are those of the faculty, and do not represent those of Academy, ACTHIV or American Nurses Credentialing Center’s Commission on Accreditation. This activity is intended as a supplement to existing knowledge, published information, and practice guidelines. Learners should appraise the information presented critically, and draw conclusions only after careful consideration of all available scientific information.

Instructions on How to Receive Credit
There are no fees to participate in the activity.  Participants must review the activity information including the learning objectives and disclosure statements, as well as the content of the activity. To receive CME/CNE credit for your participation, please complete the post-test (achieving a passing grade of 100%), and program evaluation. Your certificate will be available for printing immediately.

Hardware/Software Requirements
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© 2016. This CME/CNE -certified activity is held as copyrighted © by American Academy of CME and ACTHIV. Through this notice, the Academy and ACTHIV grant permission of its use for educational purposes only. These materials may not be used, in whole or in part, for any commercial purposes without prior permission in writing from the copyright owner(s).